The primary Objective is to demonstrate the efficacy of fremanezumab administered as monthly and quarterly subcutaneous (sc) injections to adult Chinese participants with migraine. The secondary Objectives are to further demonstrate the efficacy of fremanezumab administered as monthly and quarterly sc injections and to evaluate the safety and tolerability of fremanezumab administered as monthly and quarterly sc injections. The total study duration for participants is planned to be approximately 9 months. The study will consist of a screening visit, a baseline period (4 weeks), a 12-week double-blind treatment period, a 12-week open-label treatment period, and a follow-up period lasting approximately 3 months after the last dose of treatment.