What to Know About Schizophrenia

An overview of what schizophrenia is, how common it is worldwide, and why consistent mental health treatment can help reduce relapse risk. We also highlight some key facts that guide Teva’s scientific focus in mental health.

Schizophrenia is a chronic, debilitating mental health disorder that can significantly affect how a person thinks, feels, and acts. Symptoms vary from person to person, but common examples include: 01

  • Delusions
  • Hallucinations
  • Disorganized speech or behavior
  • Impaired cognitive ability

Schizophrenia is a chronic, progressive and severely debilitating mental disorder that affects how one thinks, feels and acts. Patients experience many symptoms, including delusions, hallucinations, disorganized speech or behavior and impaired cognitive ability. 01

How common is schizophrenia worldwide?

~24
million worldwide
3.5
million in the U.S.
 

Approximately 24 million people worldwide and 3.5 million people in the U.S. are currently diagnosed with schizophrenia. 02 03

When does schizophrenia typically begin?

Early 20s
for men
Late 20s
for women
 

Although schizophrenia can occur at any age. However, the average age of onset tends to be in the late teens to early 20s for men, and late 20s to early 30s for women. 04

Gaps in mental health treatment

Epidemiological surveys focused on schizophrenia explore how the condition affects different groups of people and why. 05
In these surveys, approximately 40% of respondents with schizophrenia reported receiving no mental health treatment in the preceding 6–12 months. 06

40percent-piechart.jpg

 

Why relapse matters in schizophrenia

Relapse is a significant and complex challenge faced by many people living with schizophrenia. Globally, relapse rates are estimated to be between 50–92%. 07 50to92percent-piechart.jpg

Each relapse can carry potentially lasting health risks, including:

Changes in brain morphology (changes to the brain's structure, shape, or volume of brain tissue) 08

Loss of day-to-day function 09

Treatment resistance 10

 

Learn more about schizophrenia

References

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    WHO Fact Sheets. Schizophrenia. https://www.who.int/news-room/fact-sheets/detail/schizophrenia [Accessed February 2026].

  2. Back to contents.

    WHO Fact Sheets. Schizophrenia. https://www.who.int/news-room/fact-sheets/detail/schizophrenia [Accessed February 2026].

  3. Back to contents.

    FHE Health. Schizophrenia Statistic. https://fherehab.com/schizophrenia/statistics [Accessed February 2026].

  4. Back to contents.

    National Institute of Mental Health. Schizophrenia. https://www.nimh.nih.gov/health/statistics/schizophrenia [Accessed February 2026].

  5. Back to contents.

    Britannica. Epidemiology. https://www.britannica.com/science/epidemiology [Accessed February 2026].

  6. Back to contents.

    National Library of Medicine. Unmet need for mental health care in schizophrenia: an overview of literature and new data from a first-admission study. https://pubmed.ncbi.nlm.nih.gov/19505994/ [Accessed February 2026].

  7. Back to contents.

    National Library of Medicine. Lifetime relapse and its associated factors among people with schizophrenia spectrum disorders who are on follow up at Comprehensive Specialized Hospitals in Amhara region, Ethiopia: a cross-sectional study. https://pmc.ncbi.nlm.nih.gov/articles/PMC8101248/ [Accessed February 2026].

  8. Back to contents.

    National Library of Medicine. Relapse Duration, Treatment Intensity, and Brain Tissue Loss in Schizophrenia: A Prospective Longitudinal MRI Study. https://pubmed.ncbi.nlm.nih.gov/23558429/ [Accessed February 2026].

  9. Back to contents.

    BMC Psychiatry 13, 50. Andreasen, N. C., et al. (2013). The nature of relapse in schizophrenia. https://www.proquest.com/openview/0638c8f7fe42c209b5094df38633b97c/1.pdf?pq-origsite=gscholar&cbl=44775 [Accessed February 2026].

  10. Back to contents.

    National Library of Medicine. Does relapse contribute to treatment resistance? Antipsychotic response in first- vs. second-episode schizophrenia. https://pubmed.ncbi.nlm.nih.gov/30514883/ [Accessed February 2026].

FAQs: Schizophrenia (science)

What is schizophrenia?

Schizophrenia is a chronic mental disorder that affects how a person thinks, feels, and acts. Symptoms of schizophrenia can include delusions, hallucinations, disorganized speech or behavior, and impaired cognitive ability.

How common is schizophrenia worldwide?

Approximately 23 million people worldwide are currently diagnosed with schizophrenia.

How many people in the U.S. have schizophrenia?

About 3.5 million people in the United States are living with schizophrenia.

When does schizophrenia usually begin?

The average onset for schizophrenia symptoms is typically in the late teens to early 20s for men and late 20s to early 30s for women. However, schizophrenia can develop earlier or later in some cases.

What does the treatment gap mean in schizophrenia?

In surveys, approximately 40% of respondents with schizophrenia reported not receiving any mental health treatment in the preceding 6–12 months.

How common is relapse in schizophrenia?

Relapse remains an ongoing challenge. Globally, an estimated 50% to 92% of people living with schizophrenia will relapse once or more.

Why does relapse matter in schizophrenia?

Each relapse can carry biological risks, including potential changes in brain morphology, loss of day-to-day function, and treatment resistance.

Where can people find stories and support resources?

People can explore lived-experience stories and educational resources through trusted mental health support platforms and healthcare providers.

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